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| First Name: | Jurgen | | Last Name: | Goetz | | Title: | Director, Alzheimer's and Parkinson's Disease Laboratory Brain and Mind Research Institute | | Affiliation: | University of Sydney | | Department: | Brain and Mind Research Institute | | Street Address 1: | 100 Mallett St. | | City: | Camperdown | | Zip/Postal Code: | NSW 2050 | Country/Territory: | Australia | | Phone: | +61-2-9351 0789 or 0799 | | Fax: | +61-2-9114-4200 |
Disclosure:
(view policy)
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Member reports no financial or other potential conflicts of interest. [Last Modified: 16 April 2007]
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View all comments by Jurgen Goetz
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Alzheimer Disease, Parkinson Disease, Tauopathies
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Animal Models, Molecular and Cell biology, Tau/Cytoskeleton, Proteomics, Neurobiology, DNA microarrays, A-beta PP/A-beta, Signal transduction, Microscopy
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Chen F, Wollmer MA, Hoerndli F, Munch G, Kuhla B, Rogaev EI, Tsolaki M, Papassotiropoulos A, Gotz J, Role for glyoxalase I in Alzheimer's disease, Proc Natl Acad Sci U S A. 2004 May 18;101(20):7687-92, PMID: 15128939
Gotz J, Streffer JR, David D, Schild A, Hoerndli F, Pennanen L, Kurosinski P, Chen F, Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy, Mol Psychiatry. 2004 Jul;9(7):664-83, PMID: 15052274
Ferrari A, Hoerndli F, Baechi T, Nitsch RM, Gotz J, beta-Amyloid induces paired helical filament-like tau filaments in tissue culture, J Biol Chem. 2003 Oct 10;278(41):40162-8. Epub 2003 Jul 31, PMID: 12893817
Gotz J, Chen F, van Dorpe J, Nitsch RM, Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils, Science. 2001 Aug 24;293(5534):1491-5, PMID: 11520988
Kins S, Crameri A, Evans DR, Hemmings BA, Nitsch RM, Gotz J, Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice, J Biol Chem. 2001 Oct 12;276(41):38193-200, PMID: 11473109
Gotz J, Tau and transgenic animal models, Brain Res Brain Res Rev. 2001 Jul;35(3):266-86, PMID: 11423157
Gotz J, Chen F, Barmettler R, Nitsch RM, Tau filament formation in transgenic mice expressing P301L tau, J Biol Chem. 2001 Jan 5;276(1):529-34, PMID: 11013246
Gotz J, Probst A, Ehler E, Hemmings B, Kues W, Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha, Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12370-5, PMID: 9770493
Gotz J, Probst A, Spillantini MG, Schafer T, Jakes R, Burki K, Goedert M, Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform, EMBO J. 1995 Apr 3;14(7):1304-13, PMID: 7729409
Hebert JM, Rosenquist T, Gotz J, Martin GR, FGF5 as a regulator of the hair growth cycle: evidence from targeted and spontaneous mutations, Cell. 1994 Sep 23;78(6):1017-25, PMID: 7923352
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